In the US, scientists at mit were able to identify the mechanism that gives the answer to the question about what can cause irreversible changes in the brain leading to the development of neurodegenerative diseases of aging properties. The researchers found that age and deteriorate the brain starts hard when its neurons there is an accumulation of short fragments of RNA.
“Accumulation in some neurons with age, short fragments of RNA, formed under oxidative stress leads to changes in the brain associated with the development of neurodegenerative diseases, the risk of which increases with aging”, – cites the opinion of scientists on MedicalXpress.
Therefore, the accumulation of short-chain RNA molecules, according to experts is a marker of susceptibility to brain ageing and neurodegenerative diseases. Because of this accumulation, as it turned out, reduces the number of synthesized proteins that are important for the functions of the Central nervous system.
The study authors observed this process in the brain of mice. Scientists have ascertained that he touched the striatum (striped body) – the brain region responsible for muscle function and is associated with Parkinson’s and Huntington’s. Accumulates in it, the RNA molecules were connected with the ribosome and prevent the synthesis of the correct proteins. The reason for such violations, researchers believe oxidative stress provoked by increased formation of reactive oxygen species in neurons.
In the human brain mechanism leading to the development of diseases of aging, scientists have observed in the frontal lobe of the cerebral cortex.
Earlier Magicforum wrote about the fact that violations of the brain can cause the passion for football in his youth.