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Scientists combined an antibiotic called rifampicin with a natural antioxidant called resveratrol, found in plants, to create the chemical cocktail. And experiments on mice were so encouraging, trials on humans are now being planned.
The rodents were genetically engineered to develop Alzheimer’s and other forms of dementia. But after they were injected through the nose with regular, tiny doses of rifampicin and resveratrol, their cognitive skills dramatically improved.
The study, at Osaka City University in Japan, also found the mice had lower levels of toxic proteins and communication between their neurons improved.
A nasal spray is now being developed by venture company Medilabo RFP.
Dementia affects over 920,000 people in the UK ‑ a figure that will rise to two million by 2050.
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