That alcohol can hinder the effect of drugs, is the most patients is not known. However, green salad, liquorice, Grapefruit, tea, milk products, and even bottled water can influence the effect of certain drugs. The chamber of pharmacists of lower Saxony clarifies the eight most common interactions and advises patients to uncertainties from the pharmacist for advice.
Interaction Point 1: Alcohol
Alcohol is a disruptive factor number One is, when it comes to interactions with drugs. Especially in the case of drugs such as sleeping pills and sedatives, antidepressants or other psychotropic drugs is to be expected with problems. Like alcohol, these drugs have a depressant effect on the Central nervous system, therefore it can come to a mutual reinforcement – in the extreme case even up to a respiratory or cardiac arrest.
Alcohol also alters the metabolism so that the drug contained active ingredients are more slowly degraded. Effects and side effects can persist longer. In the worst case, it can lead to poisoning. The Patient takes antibiotics, such as metronidazole, can cause small amounts of Alcohol Nausea, a red face and racing heart, because these drugs slow the breakdown of alcohol. Special caution is necessary when taking Paracetamol and alcohol. The alcohol reinforces the liver-damaging effects of the drug with potentially life-threatening consequences. Even with a hangover-headache, Paracetamol is therefore not a good choice.
Interaction number 2: coffee, tea, and Cola
Caffeine increases the blood pressure. This reaction is amplified when certain antibiotics, in particular, gyrase inhibitors such as fluoroquinolones, to be taken at the same time. The body can break down the caffeine and then worse. As a result, increased occurrence of tachycardia and sleeping disorders. For this reason, other sources of Caffeine, such as Black should be avoided, Green or mate tea, and Cola.
In addition to the caffeine, the tannins in tea and coffee are problematic, because the tannic acid hinders the absorption of many drug substances significantly. For example, iron is bound. The consequence of this is that it is increasingly excreted to go instead of through the bowel wall into the bloodstream. The two hour offset to the intake solves the Problem. Be drug is taken, in which a uniform blood level is elementary, as in the case of psychotropic drugs and anti-asthmatics should be avoided tannin-containing beverages completely.
Interaction Number 3: Milk Products
Many drugs that work in conjunction with Calcium significantly worse, which is included in, for example, Quark, yoghurt and milk. Especially antibiotics are not affected because the active ingredient of the antibiotic binds in the intestine to Calcium. This connection can no longer be completely absorbed, so too much active substance remains in the intestine and excreted. Particular attention osteoporosis need to be patient, for you an abundant calcium supply is necessary.
On the days where against osteoporosis bisphosphonates are taken, however, needs to be consistently dispensed with a minimum of one hour before and at least two hours after the meal on the intake of Calcium-containing products. The body can not utilize the active ingredients otherwise. Also, some medications for Parkinson’s may not be protein-containing foods combined.
Interaction # 4: Grapefruit
The Grapefruit has it all: four hours after the consumption of the fruit or juice of the metabolic behaves in terms of the effect of many drugs almost incalculable. This effect also on many hours of remains, so that a time offset intake alone is not sufficient. Therefore Grapefruit should be avoided when taking any medicine better completely. In particular, in the case of drugs against erectile dysfunction with the active ingredient Sildenafil, some Cholesterol-lowering drugs that contain the active ingredient Simvastatin, Zolpidem-containing sleeping pills or blood pressure with amlodipine and Verapamil with great caution.
Interaction # 5: Licorice
High blood pressure patients must be careful when larger amounts of licorice. The candy can lead to a change in the mineral metabolism with sodium accumulation and potassium losses. The result is Edema, i.e. water retention in the tissue and muscle in the Deposit weakness. In addition to patients with hypertension, cardiovascular patients, diabetics and Pregnant women should avoid licorice.
Interaction Number 6: Bottled Water
Some patients buy extra Calcium and iron-enriched mineral water to do something Good for yourself. However, many medicines react to these minerals, with Effect mitigation. Thus, it can be affected, for example, the efficacy of osteoporosis agents, and thyroid preparations. Medicines, take, therefore, is best with tap water. Between the taking of medicines and minerals at least two hours, patients with a view on the effectiveness of their drug to be on the safe side.
Interaction Number 7: Salad
Vitamin K by the body for blood clotting is needed. This property make use of drugs: The so-called Vitamin-K-antagonists block the action of Vitamin K and reduce blood clotting. They are used to reduce the risk of a blood clot and a stroke prevent. Patients taking blood-clotting medication, should be aware of your diet: Vitamin-K-rich foods such as lettuce, spinach, Kale, or Brussels sprouts, reduce the effect of these medicines and are best eaten only in moderation.
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